Can a runway at an international airport become misaligned like this?

Ok so. A runway 04 has is found between 036 and 045 on a compass. But can it 046 on a compass and still be numbered 04?? I'm not talking about small airstrips. I'm talking about small + mid sized to huge airports. Ones where you would see A320s and 737s. I'm a plane spotter and love to flight sim.... show more Ok so. A runway 04 has is found between 036 and 045 on a compass. But can it 046 on a compass and still be numbered 04??

I'm not talking about small airstrips. I'm talking about small + mid sized to huge airports. Ones where you would see A320s and 737s.

I'm a plane spotter and love to flight sim. I'm not a pilot I know. It's just I was looking at a chart for LFMN. That has 2 runways 04L and 04R. But both are aligned 046.
Does this occur in the real world??
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