Is there any Chemical similarity between Aspartame (C14H18N2O5) and Lisinopril (C21H31N3O5)?
I am no chemist, but I am wondering how to tell if these two substances have any chemical similarities. Aspartame is a sweetner and Lisinopril is a Blood pressure medication.
Similar in that they both caused an allergic reaction in a patient, particularly chronic months long hives outbreak and in the case of Lisinopril, also shortness of breath (patient passed out - unconcious) and nausea.
- Dr WLv 78 years agoFavourite answer
both are organic molecules
both have a benzene ring.
both have a carboxylic acid group
both have an amine group.
but.... if you're asking about pharmacological properties, the answer is no. Even tiny differences in structure can cause drastic differences in biological functions.
a common nasal decongestant
Now remove the OH group and you have d-methamphetamine. Crystal meth if prepared properly. here's a ball and stick model
the gray balls are carbon
the white ones are hydrogen
the blue is nitrogen
now locate this carbon on that model
... .. .. .. .. . .H... .this one
... .. .. .. .. .. .|..↙
C6H5CH2 - C - NHCH3
... .. .. .. .. .. .|
... .. .. .. .. . .CH3
now swap the positions of the H anc NHCH3 group and you have the other enantiomer L-methamphetamine. This is the drug found in vicks sinus inhalers. another decongestant.
now move that NH-CH3 from the back to the front
tiny changes in the chemical structure or chemical composition of organic molecules create HUGE differences in chemical and biological properties.
unrelated allergic response!