If the base sequence read GGG CTT CTT AAA instead, would this result in sickle cell hemoglobin? Explain.?
The original sickle cell was:
GGG CAT CTT TTT
- Anonymous8 years agoFavourite answer
Neither of those sequences contain the codon involved in sickle cell anaemia.
In normal HbA a GAG on the coding strand (or CTC on the template) is replaced by GTG (CAC) and so glutamic acid is replaced by valine.
I can't find either of those codons, so it is not true.