I am not sure if I will be able to help much, but I've been in similar situations before. Now, it may appear or be easy to put all of these people in the same category "controlling freaks" but it's quite possible that the reasons for their behavior have different origins and causes. A lot of "control freaks" have few things in common, however, or that is what I've experienced with them. They want someone to depend on them, they want a field they can excel in and usually a lot of bottled insecurities in others. In almost all cases there is something they are masking... It can be used as a defense mechanism and as a learned form of behavior. It's not healthy in any way.
Let's go with your boss and colleague first. I don't agree with what your boss has told you. I think that always thinking you're best can lead to losing touch with reality, missing on ways to improve yourself in any field and basically be very depressed when someone proves you wrong. As for your colleague, even if I would do the same thing probably, I get the feeling that you're actually questioning her motives and good intentions. She may have strange way of dealing with people, but that doesn't mean she knows nothing about life. The thing is you can learn valuable things from almost all people. The important thing is to avoid copying their strategies but instead analyze their attitudes. They might not be all wrong, just poorly executed.
The story with your uncle and your brother goes into family matters and those kinds of things always have strong emotional cause and reaction. They can not fall into the same category with your relationships at work. Have you tried talking to him? Is it just your brother he is having this problem with? Maybe there's more to it than it meets the eye. I am far from saying that your brother has any blame in this, but the reasons for your uncles behavior can go deep and can have to do with something more than just plain bitterness.
And as for this guy you mentioned.... I don't know. I've been puzzled a lot of times myself. I can't really say much from what you said about him here. I wouldn't dare to give you advice on how to deal with him. I mean, he obviously has some sort of connection with you that you don't share or you're even aware of. Those kinds of people can be very dangerous. Not necessarily in an aggressive sort of way, but emotionally draining.
My advice to you would be to try and live your life the best way you can. Stay true to your own principles but don't rule out any argument you receive on them. We're social beings and the key to any successful relationship is communication, with others and with ourselves. Do a "spring cleaning" of your thoughts once in a while. Remember that we're all different and try not to respond to this with anger every time.