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  • Could a common blood pressure medication inhibit the COVID-19 virus?

    Recent information about the virus states that:  "It mainly enters human cells by binding to angiotensin converting enzyme 2 (ACE2) receptors.[27]".  "ACE inhibitors inhibit the activity of angiotensin-converting enzyme, an important component of the renin–angiotensin system liable to convert angiotensin I to angiotensin II,[3] and hydrolyse bradykinin[1] Thereby, ACE inhibitors in turn decrease the formation of angiotensin II, a vasopressin, but increase the level of bradykinin, a peptide vasodilator.[3][1] This combination, thereby, is synergistic in increasing ACE inhibitors' blood pressure-lowering effect.[3][1]"

    This DOES NOT indicate a protective effect from the virus, but it may mean patients with high blood pressure may be less likely to die compared to other types of underlying conditions.

    4 AnswersMedicine4 months ago